ANTIBACTERIAL ACTIVITY PEGANUM HARMALA PDF

Where there are still existing systems on the plant plays a vital role in health care. In developed countries, drugs that are extracted from plants are also extremely important for people, currently at least chemicals derived from plant species can be considered as important drugs for human consumption [1]. An antimicrobial is a compound that kills or inhibits the growth of microbes such as bacteria. This compound is said to have an antibacterial activity [2].

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Tulabar Sample collection was done in April for leave and stem, in May for flower, in June for seed and in September for root. In a study, the alcoholic and aqueous extract of P. Beta-carboline and quinoline alkaloids in root cultures and intact plants of Peganum harmala. Reducing this germ in oral cavity can reduce the rate of tooth decays in humans. Thin Layer Chromatography can justify this difference, because hramala TLC results for seed antiibacterial root extract showed that these extracts contain several bands with different density or even some bands exist in one extract that we have not been able to find in another one.

In general, antibacterial activity of these two extracts was not considerably affected after temperature and pH treatment. So, it is likely that the active phytochemicals, which exist in root extract, interfere with cell-wall petidoglycan synthesis in bacteria more than seed extract and finally resulted in increasing of the access of colistin to the cell membrane, the outcome of this event is increasing the synergistic effect.

Introduction Nowadays, bacterial infections especially those caused by multi-drug resistant MDR bacteria have become one of the great challenges for modern healthcare.

This plant has been considered for the treatment of a variety of human ailments, such as lumbago, asthma, colic, jaundice and as a stimulant emmenagogue Bukhari antbacterial al.

Introduction Dental caries is one of the most common diseases that humans are afflicted with throughout their lives. In general, the obtained results from TLC revealed that these two parts of P. Also, pH and temperature stability of seed and root extract is important especially for treatment of brucellosis. This experiment was carried out in duplicate. It has been reported that harmane as a highly aromatic planar alkaloid exerts its antibacterial activity through interchalate with DNA Cowan, [ 12 ]thus, this antibacterial mechanism must be considered for active extract of Peganu.

Also, all of the tested bacteria were resistant to colistin. There are various reports that P. Antimicrobial Activity of Peganum Harmala L.

National Center for Biotechnology InformationU. The lawn culture was prepared by sterile cotton swab and allowed to remain in contact for 1 min. Active extract was fractioned using Thin Layer Chromatography; also their synergism activity in combination with synthetic antibiotic was evaluated.

This process was repeated for three times. For instance, pH stability is important in the treatment of brucellosis, one of the most important factors for the treatment of brucellosis is that the antibiotic should be able to act under acidic condition pH 5 in phagolysosomes of macrophages because brucellae grow and replicate in this pH value Akova et al.

There was a problem providing the content you requested Since the ancient time, the idea of finding healing powers in plants has been noteworthy. Also, the retardation factor R f values of the spots were determined. Antileishmanial activity of Peganum harmala extract on the in vitro growth of Leishmania major promastigotes in comparison to a trivalent antimony drug. Antibacterial activity of the root extract against tested Antibaccterial species and S.

Among the evaluated parts of P. Plants produce a vast array of secondary metabolites that in many cases, these substances act as defense mechanisms against predation by herbivores, microorganisms and insects; also similar substances can be produced by plants as a part of their normal growth and development peganuum in response to stress Mirjana et al. It seems essential to investigate other antimicrobial agents that have inhibitory effect on relevant microorganisms in oral and dental diseases with fewer side effects compared to chlorhexidine.

Efficient in vitro multiplication of Syrian Rue Peganum harmala L. Toxicity of Peganum harmala: More studies concerning about the molecular basis of this interaction must be performed in future. Most 10 Related.

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ANTIBACTERIAL ACTIVITY PEGANUM HARMALA PDF

Tulabar Sample collection was done in April for leave and stem, in May for flower, in June for seed and in September for root. In a study, the alcoholic and aqueous extract of P. Beta-carboline and quinoline alkaloids in root cultures and intact plants of Peganum harmala. Reducing this germ in oral cavity can reduce the rate of tooth decays in humans. Thin Layer Chromatography can justify this difference, because hramala TLC results for seed antiibacterial root extract showed that these extracts contain several bands with different density or even some bands exist in one extract that we have not been able to find in another one. In general, antibacterial activity of these two extracts was not considerably affected after temperature and pH treatment. So, it is likely that the active phytochemicals, which exist in root extract, interfere with cell-wall petidoglycan synthesis in bacteria more than seed extract and finally resulted in increasing of the access of colistin to the cell membrane, the outcome of this event is increasing the synergistic effect.

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Peganum harmala is a famous medicinal plant used in the Iranian traditional medicine, due to the antimicrobial compounds found in its seeds and roots. Objectives: The main objective of the present study was to investigate the antibacterial activities of alcoholic extracts of P. Micro-broth dilution method was employed to evaluate the antimicrobial effects of the extract on MRSA strains. HEK cells were exposed to different concentrations of ethanolic extract of P. Results: The minimum inhibitory concentration of P. The most antibacterial activity of the extract was found to be at

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